Microscopic genetic analysis of tissue, manual, each additional multiplex stain procedure
Medicare pricing data for 2,629 providers across 47 states
Prices vary significantly by location — from $60 in West Virginia to $394 in Puerto Rico. Where you get this procedure matters more than almost any other factor. Note: These costs reflect the Medicare physician/supplier component. Hospital facility fees are billed separately and can be 2-5x the physician fee.
💡 What You Should Know
Microscopic genetic analysis of tissue, manual, each additional multiplex stain procedure (HCPCS code 88377) is a medical procedure billed to Medicare. The average Medicare-allowed cost is $174.35, but hospitals typically charge $577.52 — a 3.3x markup. Prices vary significantly by state and provider.
🏷️ Typical Out-of-Pocket Cost
Medicare patients typically pay about 20% of the allowed amount as coinsurance. Based on the average allowed cost of $174.35, your out-of-pocket cost would be approximately $34.87. Actual costs depend on your specific plan, deductible, and whether you've met your annual out-of-pocket maximum.
What Hospitals Charge vs. What Medicare Pays
Hospitals charge 3.3x more than what Medicare allows for this procedure. Medicare actually pays $138.78 on average.
Cost by State
Medicare-allowed amounts vary significantly by state
| State | Allowed Cost | Hospital Charge | Providers | Services | vs. National |
|---|---|---|---|---|---|
| Puerto Rico | $394 | $428 | 8 | 46 | +125.9% |
| Connecticut | $366 | $1,370 | 32 | 3,253 | +109.8% |
| New Jersey | $296 | $1,125 | 70 | 14,926 | +69.8% |
| New York | $257 | $1,217 | 167 | 12,626 | +47.4% |
| South Dakota | $197 | $200 | 1 | 14 | +12.9% |
| Texas | $197 | $498 | 203 | 10,790 | +12.7% |
| California | $178 | $464 | 366 | 29,606 | +2.4% |
| Arizona | $148 | $287 | 75 | 7,209 | -15.0% |
| Wisconsin | $136 | $608 | 31 | 278 | -21.8% |
| Tennessee | $134 | $319 | 141 | 2,747 | -22.9% |
| Maryland | $133 | $432 | 43 | 378 | -23.9% |
| Massachusetts | $131 | $486 | 72 | 1,518 | -24.8% |
| Illinois | $127 | $343 | 113 | 3,764 | -27.4% |
| New Mexico | $122 | $459 | 17 | 625 | -30.2% |
| Washington | $116 | $243 | 99 | 6,992 | -33.4% |
| Florida | $114 | $370 | 177 | 7,234 | -34.6% |
| Hawaii | $111 | $237 | 24 | 242 | -36.1% |
| Georgia | $106 | $264 | 31 | 5,533 | -39.3% |
| Minnesota | $100 | $452 | 116 | 2,405 | -42.9% |
| Nebraska | $99 | $242 | 7 | 107 | -43.3% |
| Missouri | $98 | $424 | 48 | 1,164 | -43.7% |
| Virginia | $98 | $479 | 54 | 3,928 | -43.7% |
| Oklahoma | $93 | $303 | 11 | 137 | -46.7% |
| Montana | $89 | $193 | 3 | 252 | -49.1% |
| Oregon | $88 | $261 | 17 | 266 | -49.3% |
| Ohio | $87 | $377 | 102 | 1,710 | -50.0% |
| North Carolina | $87 | $325 | 54 | 616 | -50.2% |
| Louisiana | $86 | $200 | 46 | 1,050 | -50.9% |
| Alaska | $84 | $651 | 6 | 18 | -51.9% |
| Colorado | $82 | $207 | 58 | 610 | -53.2% |
| Kansas | $79 | $256 | 24 | 282 | -54.5% |
| Michigan | $76 | $348 | 36 | 632 | -56.2% |
| Pennsylvania | $72 | $399 | 90 | 3,091 | -58.5% |
| South Carolina | $72 | $308 | 35 | 628 | -58.8% |
| Indiana | $72 | $251 | 32 | 1,220 | -58.9% |
| Alabama | $70 | $332 | 43 | 358 | -59.7% |
| Iowa | $70 | $259 | 18 | 402 | -59.8% |
| Arkansas | $68 | $256 | 42 | 754 | -60.9% |
| Mississippi | $67 | $287 | 11 | 137 | -61.3% |
| New Hampshire | $66 | $207 | 2 | 13 | -62.0% |
| Kentucky | $66 | $161 | 9 | 1,150 | -62.0% |
| Maine | $65 | $190 | 27 | 757 | -62.6% |
| Rhode Island | $63 | $170 | 9 | 106 | -63.7% |
| Utah | $63 | $264 | 16 | 172 | -64.0% |
| North Dakota | $62 | $369 | 8 | 55 | -64.5% |
| Vermont | $62 | $369 | 6 | 39 | -64.7% |
| West Virginia | $60 | $819 | 7 | 58 | -65.3% |
⚠️ Important: These costs reflect the Medicare physician/supplier component. Hospital facility fees may be billed separately. Total out-of-pocket costs may be higher.
💊 Need post-procedure medications? Check costs on OpenPrescriber